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2 results for: Bisphenol A, Male Reproductive System — WEEK 7

The weeks shown in color represent the start and end points of chemical exposure for each study.
Study Results Study Details References

Results for Bisphenol A

Increased anogenital distance and decreased epididymal weight

Subjects: CD-1 mice

Chemical: Bisphenol A

Low doses tested: 50 μg/kg bw/d

Route of administration: dissolved in corn oil and fed orally

Exposure duration: gestational day 16 – gestational day 18 (comparable to human prenatal development from approximately day 1 of week 7 to day 1 of week 11)

Age of measurement: 3, 21 and 60 days of age

 Reference [PubMed Link]
Gupta C. 2000. Reproductive malformation of the male offspring following maternal exposure to estrogenic chemicals. Proceedings of the Society of Experimental Biology & Medicine 224(2):61-68.
Study Results Study Details References

Results for Bisphenol A

Increased prostate weight and induced androgen receptor binding activity

Subjects: CD-1 mice

Chemical: Bisphenol A

Low doses tested: 50 μg/kg bw/d

Route of administration: dissolved in corn oil and fed orally

Exposure duration: gestational day 16 – gestational day 18 (comparable to human prenatal development from approximately day 1 of week 7 to day 1 of week 11)

Age of measurement: 3, 21 and 60 days of age

 Reference [PubMed Link]
Gupta C. 2000. Reproductive malformation of the male offspring following maternal exposure to estrogenic chemicals. Proceedings of the Society of Experimental Biology & Medicine 224(2):61-68.