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1 result for: Bisphenol A, Endocrine System — WEEK 4

The weeks shown in color represent the start and end points of chemical exposure for each study.
Study Results Study Details References

Results for Bisphenol A

Decreased luteinizing hormone in first generation males at 1.2 μg/kg; decreased testosterone, estradiol and follicle-stimulating hormone in first generation males at both doses

Subjects: Holtzman rats

Chemical: Bisphenol A

Low doses tested: 1.2 or 2.4 μg/kg bw/d

Route of administration: delivered via gavage

Exposure duration: gestational day 12 – post-natal day 21 (comparable to human prenatal development from approximately day 1 of week 4 to beyond birth)

Age of measurement: birth through adulthood

 Reference [PubMed Link]
Salian S, Doshi T, Vanage G. 2009. Perinatal exposure of rats to Bisphenol A affects the fertility of male offspring. Life Sci 85(21-22):742-752.