The weeks shown in color represent the start and end points of chemical exposure for each study.
| Study Results | Study Details | References |
Results for Dioxin (TCDD)Decreased number and density of nodules. |
Subjects: Fetal calvaria cells of rats Chemical: Dioxin (TCDD) Low doses tested: 10 nM Route of administration: in vitro culture Exposure duration: gestational day 21 – in vitro culture (comparable to human prenatal development from approximately day 1 of week 15 to day 1 of week 18) Age of measurement: 6, 8, 10 and 21 days in culture |
Reference [PubMed Link] Gierthy JF, Silkworth JB, Tassinari M, Stein GS, Lian JB. 1994. 2,3,7,8-tetrachlorodibenzo-p-dioxin inhibits differentiation of normal diploid rat osteoblasts in vitro. J Cell Biochem 54(2):231-238. |