The weeks shown in color represent the start and end points of chemical exposure for each study.
| Study Results | Study Details | References |
Results for ChlorpyrifosIncreased cholesterol and triglyceride levels in males; increased insulin levels in non-fasted males |
Subjects: Sprague-Dawley rats Chemical: Chlorpyrifos Low doses tested: 1.0 mg/kg bw/d Route of administration: dissolved in DMSO and injected subcutaneously Exposure duration: post-natal day 1 – post-natal day 4 (comparable to human prenatal development from approximately day 1 of week 20 to day 1 of week 25) Age of measurement: 110 days of age |
Reference [PubMed Link] Slotkin TA, Brown KK, Seidler FJ. 2005. Developmental exposure of rats to chlorpyrifos elicits sex-selective hyperlipidemia and hyperinsulinemia in adulthood. Environ Health Perspect 113(10):1291-1294. |